The
early part of 2018 has seen an increase in the number of requests
for information on Duodenal Polyps. Information received by patients
with FAP has been very varied and so confusing. We do however accept
that the views of consultants can differ and that not all cases
are the same.
We
have decided to try and improve the information available by giving
links to respected articles from reliable sources. These will open
in a new page.
Gut
is a leading international journal in gastroenterology and hepatology
and has an established reputation for publishing first class clinical
research of the alimentary tract, the liver, biliary tree and pancreas.
Gut delivers up-to-date, authoritative, clinically oriented coverage
in all areas of gastroenterology and hepatology. Regular features
include articles describing novel mechanisms of disease and new
management strategies, both diagnostic and therapeutic, likely to
impact on clinical practice within the foreseeable future by leading
authorities.
Familial
adenomatous polyposis (FAP) is one of two well described forms of
hereditary colorectal cancer. The primary cause of death from this
syndrome is colorectal cancer which inevitably develops usually
by the fifth decade of life. Screening by genetic testing and endoscopy
in concert with prophylactic surgery has significantly improved
the overall survival of FAP patients. However, less well appreciated
by medical providers is the second leading cause of death in FAP,
duodenal adenocarcinoma. This review will discuss the clinicopathological
features, management, and prevention of duodenal neoplasia in patients
with familial adenomatous polyposis. Link to article http://gut.bmj.com/content/54/7/1034
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